HealthData.Gov
Blending science and compassion: The 30th educational symposium of the Society of Critical Care Medicine, San Francisco, USA, 10-14 February 2001
Updated Oct 29, 2026
HealthData.Gov
Background Checklists for peer review aim to guide referees when assessing the quality of papers, but little evidence exists on the extent to which referees agree when evaluating the same paper. The aim of this study…
Updated Oct 29, 2026
HealthData.Gov
Background Despite the medical importance of trichomoniasis, little is known about the genetic relatedness of Trichomonas vaginalis strains with similar biological characteristics. Furthermore, the distribution of…
Updated Oct 29, 2026
HealthData.Gov
Background Sequestration of transcription factors in the membrane is emerging as an important mechanism for the regulation of gene expression. A handful of membrane-spanning transcription factors has been previously…
Updated Oct 29, 2026
HealthData.Gov
Background Gene disruption by targeted integration of transfected constructs becomes increasingly popular for studies of gene function. The chicken B cell line DT40 has been widely used as a model for gene knock-outs…
Updated Oct 29, 2026
HealthData.Gov
Background The cyclin-dependent kinase inhibitor p27 is a putative tumor suppressor that is downregulated in the majority of human prostate cancers. The mechanism of p27 down-regulation in prostate cancers in unknown,…
Updated Oct 29, 2026
HealthData.Gov
Background Tuberculosis (TB) is an established occupational disease affecting health care workers (HCWs). Determining the risk of TB among HCWs is important to enable authorites to take preventative measures in health…
Updated Oct 29, 2026
HealthData.Gov
The kinetics of apoptosis and the apoptosis-regulating gene p53 in adjuvant arthritis (AA) were investigated to assess the value of the AA rat model for testing apoptosis-inducing therapies. Very few terminal…
Updated Oct 29, 2026
HealthData.Gov
To determine whether IL-4 is therapeutic in treating established experimental arthritis, a recombinant adenovirus carrying the gene that encodes murine IL-4 (Ad-mIL-4) was used for periarticular injection into the ankle…
Updated Oct 29, 2026
HealthData.Gov
Background and Purpose Stroke, increasingly referred to as a "brain attack", is one of the leading causes of death and the leading cause of adult disability in the United States. It has recently been estimated that…
Updated Oct 29, 2026
HealthData.Gov
Background Toward the goals of providing an additional vector to add to the armamentarium available to HIV vaccinologists and of creating a bivalent vaccine effective against dengue virus and HIV, we have attempted to…
Updated Oct 29, 2026
HealthData.Gov
Chronic heart failure (CHF) is a common condition with a poor prognosis. It is associated with poor exercise tolerance and debilitating symptoms. These symptoms appear to be associated with pathophysiological changes…
Updated Oct 29, 2026
HealthData.Gov
Background Filopodia, retraction fibers and microvilli, are fragile microextensions of the plasma membrane that are easily damaged by mechanical force during specimen preparation for microscopy. To preserve these…
Updated Oct 29, 2026
HealthData.Gov
Background Although guidelines for critical appraisal of diagnostic research and meta-analyses have already been published, these may be difficult to understand for clinical researchers or do not provide enough detailed…
Updated Oct 29, 2026
HealthData.Gov
Background The most important receptor for nitic oxide is the soluble guanylate cyclase (sGC), a heme containing heterodimer. Recently, a pyrazolopyridine derivative BAY 41-2272, structurally related to YC-1, was…
Updated Oct 29, 2026
HealthData.Gov
Background The Apo-1/Fas (CD95) molecule is an apoptosis-signaling cell surface receptor belonging to the tumor necrosis factor (TNF) receptor family. Both Fas and Fas ligand (FasL) are expressed in activated mature T…
Updated Oct 29, 2026
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Background: A inverse correlation has been found between changes in ionized calcium concentrations and the addition of albumin in vitro, which may explain adverse cardiovascular effects attributed to exogenous albumin…
Updated Oct 29, 2026
HealthData.Gov
Background The EST database provides a rich resource for gene discovery and in silico expression analysis. We report a novel computational approach to identify co-expressed genes using EST database, and its application…
Updated Oct 29, 2026
HealthData.Gov
Cytokines and direct cell contact in synovitis: relevance to therapeutic intervention
Updated Oct 29, 2026
HealthData.Gov
Background Acyclovir (ACV) resistant herpes simplex virus (HSV) isolates can be readily selected in animal infection models receiving suboptimal ACV treatment, however no comparative studies of the emergence of…
Updated Oct 29, 2026