HealthData.Gov
The adaptor protein p130Cas(Cas) has been shown to be involved in different cellular processes including cell adhesion, migration and transformation. This protein has a substrate domain with up to 15 tyrosines that are…
HealthData.Gov
The Congress took place at the northernmost academic center in the world, in the state-of-the art Tromso University Hospital. There were over 500 participants, mainly from Scandinavian countries, with approximately 50…
HealthData.Gov
Carotenoid pigments are largely distributed in nature. They are present in all of the photosynthetic organisms as well as in some bacteria, fungi, and yeast [1]. Two major biological roles have been assigned to…
HealthData.Gov
Cellular senescence is a defining property of euploid cells in culture [1,2]. Cultures derived from cells explanted from tissues of a variety of animal species exhibit a finite number of population doublings before…
HealthData.Gov
TheTnfrh1gene (gene symbolTnfrsf23) is located near one end of a megabase-scale imprinted region on mouse distal chromosome 7, about 350 kb distant from the nearest known imprinting control element. Within 20 kb…
HealthData.Gov
Although various endothelium-dependent relaxing factors (endothelial autacoids) are released upon the elevation of endothelial cytosolic free Ca2+concentration (EC [Ca2+]i), the quantitative relationship between EC…
HealthData.Gov
EnteropathogenicCampylobacter jejuniandC. coliare presently the most common cause of acute bacterial gastroenteritis in the developed world. An understanding of sources and means of transmission ofCampylobacteris an…
HealthData.Gov
Thefrizzledpathway in Drosophila has been studied intensively for its role in the development of planar polarity in wing hairs, thoracic bristles and ommatidia. Selected cells in the arista (the terminal segment of the…
HealthData.Gov
AllChlamydiaspecies are obligate intracellular bacterial parasites, and all are pathogenic to their various hosts [1].Chlamydia trachomatisandChlamydia pneumoniaeare human pathogens; the former being the etiologic agent…
HealthData.Gov
Community-acquired meningitis is associated with high morbidity and mortality. The epidemiology of community-acquired meningitis has changed over the past 15 years with the use of new vaccines and with the development…
HealthData.Gov
The number of Nudix hydrolase family members varies widely among different organisms. In order to understand the reasons for the particular spectrum possessed by a given organism, the substrate specificity and function…
HealthData.Gov
The active hormonal form of vitamin D (1,25-dihydroxyvitamin D) is the primary regulator of intestinal calcium absorption efficiency. In vitamin D deficiency, intestinal calcium absorption is low leading to an increased…
HealthData.Gov
In one of the biggest dilemmas facing cardiovascular clinical research, clinical trials are increasingly being required to show benefits on clinical end-points rather than surrogate end-points, while at the same time…
HealthData.Gov
Percutaneous tracheostomy (PT) has gained an increasing acceptance as an alternative to the conventional surgical tracheostomy (ST). In experienced hands, and with proper patient selection, it is safe, easy and quick.
HealthData.Gov
Today's Kinetoplastida form a diverse order of flagellated protozoans that have evolved from an ancient lineage, rooted near the base of the eukaryotic tree. The disease caused by some species of the Order…
HealthData.Gov
The tradition of circulating research findings before peerreview is old and continues today. In addition to the informal circulation of non-peer-reviewed research reports between scientists, there are also…
HealthData.Gov
From its origins in the 16thcentury, microscopy has allowed the cell, as the basic unit of eukaryotic life and disease, to be identified and analyzed. Today, quantitative cytometric technologies, either microscope based…
HealthData.Gov
The 5'-terminal cap structure plays an important role in many aspects of mRNA metabolism. Capping enzymes encoded by viruses and pathogenic fungi are attractive targets for specific inhibitors. There is a large body of…
HealthData.Gov
Cytokines play a critical role in regulating lymphoid cell responses to most antigenic stimuli, and it is therefore very likely that these molecules profoundly affect the pathogenesis of autoimmune diseases.…
HealthData.Gov
SinceMycobacterium aviumsubspeciesparatuberculosis(MAP) was isolated from intestinal tissue of a human patient suffering Crohn's disease, a controversial discussion exists whether MAP have a role in the etiology of…