HealthData.Gov
The software tool PRESTA (PRomoter EST Association) is designed for efficient recovery of characterized and partially verified promoters from GenBank and EMBL libraries. The PRESTA algorithm demonstrates the principle…
Updated Oct 29, 2026
HealthData.Gov
Background Monolysocardiolipin acyltransferase (MLCL AT) catalyzes the acylation of monolysocardiolipin to cardiolipin in mammalian tissues. We previously reported that cardiac cardiolipin levels, MLCL AT and…
Updated Oct 29, 2026
HealthData.Gov
Background A prospective observational study was done to describe nonbacterial pulmonary complications in hospitalized patients with human immunodeficiency virus (HIV) infection. Methods The study included 1,225…
Updated Oct 29, 2026
HealthData.Gov
Background Ribosomal 16S DNA sequences are an essential tool for identifying and classifying microbes. High-throughput DNA sequencing now makes it economically possible to produce very large datasets of 16S rDNA…
Updated Oct 29, 2026
HealthData.Gov
Background: Hepatic injury after ischemia/reperfusion is attributed to the development of oxygen free radical (OFR)-mediated lipid peroxidation - a process that can be measured through its byproducts, specifically…
Updated Oct 29, 2026
HealthData.Gov
Background A standardised technique using a suction-induced mini-erosion that allows serial sampling of dermal interstitial fluid (IF) for 5 to 6 days has been described. In the present study, we studied permeability…
Updated Oct 29, 2026
HealthData.Gov
The upper airway is an organ not often investigated. Relatively little is known about its complex functions, and misunderstandings abound. The paper by Thomachot et al in this issue provides an opportunity to ponder on…
Updated Oct 29, 2026
HealthData.Gov
According to the Frank-Starling relationship, a patient is a 'responder' to volume expansion only if both ventricles are preload dependent. Mechanical ventilation induces cyclic changes in left ventricular (LV) stroke…
Updated Oct 29, 2026
HealthData.Gov
Background Agitated or violent patients constitute 10% of all emergency psychiatric treatment. Management guidelines, the preferred treatment of clinicians and clinical practice all differ. Systematic reviews show that…
Updated Oct 29, 2026
HealthData.Gov
Background The potential for transmission of blood-borne pathogens such as hepatitis B virus from infected healthcare workers to patients is an important and difficult issue facing healthcare policymakers…
Updated Oct 29, 2026
HealthData.Gov
Echocardiography: a fundamental part of the intensive care curriculum
Updated Oct 29, 2026
HealthData.Gov
Backgroud Bone mineral density (BMD) is a marker of long-term estrogen exposure. BMD measurement has been used in this context to investigate the association of estrogen with breast cancer risk in three cohorts. In…
Updated Oct 29, 2026
HealthData.Gov
Human leucocyte antigen (HLA) class II molecules have been shown to be associated with predisposition to rheumatoid arthritis (RA). We generated HLA-DR and DQ transgenic mice that lacked endogenous class II molecules to…
Updated Oct 29, 2026
HealthData.Gov
Background In this study, we investigated the mechanism(s) by which delta opioids induce their potent activation of extracellular signal-regulated protein kinases (ERKs) in different cell lines expressing the cloned…
Updated Oct 29, 2026
HealthData.Gov
Background The potential role of oral vaccination of dogs against rabies in the Philippines was investigated in terms of safety and efficacy. Methods Prior to the vaccination campaign, a house-to-house survey was…
Updated Oct 29, 2026
HealthData.Gov
Background Information on the effectiveness of elementary school level, tobacco-use prevention programs is generally limited. This study assessed the impact of a structured, one-time intervention that was designed to…
Updated Oct 29, 2026
HealthData.Gov
Nutritional support has become a routine part of the care of the critically ill patient. It is an adjunctive therapy, the main goal of which is to attenuate the development of malnutrition, yet the effectiveness of…
Updated Oct 29, 2026
HealthData.Gov
Genes in the human leukocyte antigen (HLA) region remain the most powerful disease risk genes in rheumatoid arthritis (RA). Several allelic variants of HLA-DRB1 genes have been associated with RA, supporting a role for…
Updated Oct 29, 2026
HealthData.Gov
Background The Rel/NF-κB transcription factors have been shown to regulate apoptosis in different cell types, acting as inducers or blockers in a stimuli- and cell type-dependent fashion. One of the Rel/NF-κB subunits,…
Updated Oct 29, 2026
HealthData.Gov
Despite much information on their catalytic properties and gene regulation, we actually know very little of what matrix metalloproteinases (MMPs) do in tissues. The catalytic activity of these enzymes has been…
Updated Oct 29, 2026