HealthData.Gov
Background The search for an optimal experimental model in pharmacology is recently focused on (mini)pigs as they seem not only to be an alternative source of cells and tissues for xenotherapy but also an alternative…
Updated Oct 29, 2026
HealthData.Gov
Introduction: Clinically useful predictions of end-organ function and failure in severe sepsis may be possible through analyzing the interactions among demographics, physiologic parameters, standard laboratory tests,…
Updated Oct 29, 2026
HealthData.Gov
Background Recently many long-term prospective studies have involved serial collection and storage of blood or tissue specimens. This has spurred nested case-control studies that involve testing some specimens for…
Updated Oct 29, 2026
HealthData.Gov
Background Previous work, by us and others, has shown that mammalian galectins-1 have a growth-inhibitory activity for mammalian cells which is apparently independent of their β-galactoside binding site. Results We have…
Updated Oct 29, 2026
HealthData.Gov
Background Diabetes has been identified as one of the national health priority areas in Australia. After 20 years of diabetes most patients can be expected to develop diabetic retinopathy which, if undetected, is likely…
Updated Oct 29, 2026
HealthData.Gov
Background Icodextrin is a high molecular weight, starch-derived glucose polymer, which is capable of inducing sustained ultrafiltration over prolonged (12–16 hour) peritoneal dialysis (PD) dwells. The aim of this study…
Updated Oct 29, 2026
HealthData.Gov
Background In the Confidential Enquiry into Maternal Deaths (CEMD) Report, the very high risk of mortality in women who refuse blood transfusions is highlighted. The objectives were to establish current knowledge about,…
Updated Oct 29, 2026
HealthData.Gov
Background The genome of invertebrates is rich in retroelements which are structurally reminiscent of the retroviruses of vertebrates. Those containing three open reading frames (ORFs), including an env-like gene, may…
Updated Oct 29, 2026
HealthData.Gov
The role of X-chromosome inactivation in female predispositionto autoimmunity
Updated Oct 29, 2026
HealthData.Gov
Focusing on diffuse (interstitial) lung disease: a rapidly evolving field
Updated Oct 29, 2026
HealthData.Gov
Background To maintain populations of microbial cells under controlled conditions of growth and environment for an indefinite duration is a prerequisite for experimentally evolving natural isolates of wild-type species…
Updated Oct 29, 2026
HealthData.Gov
Osteoporosis is associated with low bone mass and microarchitectural deterioration of bone tissue with clinical manifestation of low trauma fractures. Rheumatoid arthritis (RA) is a risk factor due to generalized and…
Updated Oct 29, 2026
HealthData.Gov
Background The association of insulin-dependent diabetes mellitus (IDDM) and celiac disease (CD) has been widely reported in children but the relationship between the two conditions is incompletely understood. Moreover,…
Updated Oct 29, 2026
HealthData.Gov
Background Rab GTPases are regulators of intracellular membrane traffic. The Rab27 subfamily consists of Rab27a and Rab27b. Rab27a has been recently implicated in Griscelli Disease, a disease combining partial albinism…
Updated Oct 29, 2026
HealthData.Gov
Background Genomic sequence analyses have shown that horizontal gene transfer occurred during the origin of eukaryotes as a consequence of symbiosis. However, details of the timing and number of symbiotic events are…
Updated Oct 29, 2026
HealthData.Gov
Background Fabry disease is an X-linked recessive lysosomal storage disease resulting in the cellular accumulation of globotriaosylceramide particularly globotriaosylceramide. The disease is characterized by a dilated…
Updated Oct 29, 2026
HealthData.Gov
Background A previous report showed that the atypical neuroleptic clozapine resulted in marked changes in urodynamic parameters and greatly inhibited the activity of the external urethral sphincter in anesthetized rats.…
Updated Oct 29, 2026
HealthData.Gov
Background The Colchis is one of the species-rich refugia and a centre of biological diversity in western Eurasia. We analysed patterns of richness, endemism and invasions in relation to taxonomy (family membership),…
Updated Oct 29, 2026
HealthData.Gov
To determine whether IL-4 is therapeutic in treating established experimental arthritis, a recombinant adenovirus carrying the gene that encodes murine IL-4 (Ad-mIL-4) was used for periarticular injection into the ankle…
Updated Oct 29, 2026
HealthData.Gov
Background and Purpose Stroke, increasingly referred to as a "brain attack", is one of the leading causes of death and the leading cause of adult disability in the United States. It has recently been estimated that…
Updated Oct 29, 2026