HealthData.Gov
Background SFHR (small fragment homologous replacement)-mediated targeting is a process that has been used to correct specific mutations in mammalian cells. This process involves both chemical and cellular factors that…
Updated Oct 29, 2026
HealthData.Gov
Background Very low birthweight, i.e. a birthweight < 1500 g, is among the strongest determinants of infant mortality and childhood morbidity. To develop primary prevention approaches to VLBW birth and its sequelae,…
Updated Oct 29, 2026
HealthData.Gov
Background Protein kinase C (PKC) has become a major focus among cell biologists interested in second-messenger signal transduction and much has been learned about differences in the cellular localization and function…
Updated Oct 29, 2026
HealthData.Gov
Background Differences in the management of coronary artery disease between men and women have been reported in the literature. There are few studies of potential inequalities of treatment that arise from a primary care…
Updated Oct 29, 2026
HealthData.Gov
A tragic compromise on stem cell derivation
Updated Oct 29, 2026
HealthData.Gov
Background Identification of co-regulated genes is essential for elucidating transcriptional regulatory networks and the function of uncharacterized genes. Although co-regulated genes should have at least one common…
Updated Oct 29, 2026
HealthData.Gov
Background: Infections after severe brain injury or polytrauma are still a problem, and may be the result of a brain-mediated disturbed systemic immunoreactivity. The mechanism that connects initial brain affection and…
Updated Oct 29, 2026
HealthData.Gov
Respirable antisense oligonucleotides (RASONs), which attenuate specific disease-associated mRNAs, represent a new class of respiratory therapeutics with considerable potential. RASONs overcome previous obstacles that…
Updated Oct 29, 2026
HealthData.Gov
Can we speed up the online publishing process? And who will pay for it, anyway?
Updated Oct 29, 2026
HealthData.Gov
Systemic lupus erythematosus is the prototype multisystem autoimmune disease. A strong genetic component of susceptibility to the disease is well established. Studies of murine models of systemic lupus erythematosus…
Updated Oct 29, 2026
HealthData.Gov
Background We evaluated the cost-effectiveness of the WINGS project, an intervention to prevent HIV and other sexually transmitted diseases among urban women at high risk for sexual acquisition of HIV. Methods We used…
Updated Oct 29, 2026
HealthData.Gov
Background Recent electroconvulsive therapy (ECT) efficacy studies of right unilateral (RUL) ECT may not apply to real life clinics with a wide range of patients with major depressive episodes. Methods The study…
Updated Oct 29, 2026
HealthData.Gov
Background So far the prevalence of viral hepatitis infection in hospitalized patients has not been extensively studied. Therefore we conducted the present five-year observational study to evaluate the prevalence of HBV…
Updated Oct 29, 2026
HealthData.Gov
Background Evidence from recent literature shows that protocol-directed extubation is a useful approach to liberate patients from mechanical ventilation (MV). However, research evidence does not necessarily provide…
Updated Oct 29, 2026
HealthData.Gov
Weight loss is typically found during severe infections, e.g. septic arthritis. The aim of our study was to evaluate the role of leptin, regulator of food intake and energy expenditure, for the development of…
Updated Oct 29, 2026
HealthData.Gov
Background Low molecular weight heparins hold several advantages over unfractionated heparin including convenience of administration. Enoxaparin is one such heparin licensed in the UK for use in unstable coronary artery…
Updated Oct 29, 2026
HealthData.Gov
Background Recent cadaver studies show stability against axial rotation with a cylindrical cage is marginally superior to a rectangular cage. The purpose of this biomechanical study in cadaver spine was to evaluate the…
Updated Oct 29, 2026
HealthData.Gov
Statins reduce mortality of patients with coronary artery disease (CAD). However, by protocol, trials have excluded patients with chronic heart failure. Since the prevalent etiology of heart failure is CAD, preventing…
Updated Oct 29, 2026
HealthData.Gov
Objectives This study examined condom acquisition by persons in a hospital setting when single versus assorted brand name condoms were provided. Methods Condom receptacles were placed in exam rooms of two clinics.…
Updated Oct 29, 2026
HealthData.Gov
Background The intrarenal natriuretic hormone dopamine (DA) is metabolised by catechol-O-methyltransferase (COMT) and monoamine oxidase (MAO). Inhibition of COMT, as opposed to MAO, results in a potent natriuretic…
Updated Oct 29, 2026