HealthData.Gov
Background The "integrated safety report" of the drug registration files submitted to health authorities usually summarizes the rates of adverse events observed for a new drug, placebo or active control drugs by pooling…
Updated Oct 29, 2026
HealthData.Gov
Transgenic mice overexpressing IFN-γ in the epidermis develop an inflammatory skin disease resembling cutaneous lupus erythematosus shortly after birth. By 3 months of age, most female transgenics develop a lupus-like…
Updated Oct 29, 2026
HealthData.Gov
Background Although closely related, the alpha-proteobacteria Wolbachia and the Rickettsiacae (Rickettsia and Ehrlichia), employ different evolutionary life history strategies. Wolbachia are obligate endocellular…
Updated Oct 29, 2026
HealthData.Gov
Background The objective of the present study was to examine the prognostic and predictive significance of the apoptosis-related marker Fas ligand (FasL):Fas ratio in breast cancer. Methods Tumour biopsies from 215…
Updated Oct 29, 2026
HealthData.Gov
Background Hydrophobic polystyrene is the most common material for solid phase immunoassay. Proteins are immobilized on polystyrene by passive adsorption, which often causes considerable denaturation. Biological…
Updated Oct 29, 2026
HealthData.Gov
In 44 consecutive patients with systemic sclerosis (SSc), plasma concentrations of von Willebrand factor (vWf) were higher than those of the vWf propeptide, but the propeptide showed less variability within patient…
Updated Oct 29, 2026
HealthData.Gov
Mitotic death is a delayed response of p53 mutant tumours that are resistant to genotoxic damage. Questions surround why this response is so delayed and how its mechanisms serve a survival function. After uncoupling…
Updated Oct 29, 2026
HealthData.Gov
Background Schönlein-Henoch purpura is a systemic vasculitis that affects vessels of a small caliber and rarely reported in the literature. Case presentation We report on a 35-year-old woman who developed palpable…
Updated Oct 29, 2026
HealthData.Gov
Pulmonary embolism (PE) is one of the leading causes of in-patient hospital deaths. As a consequence, the identification of hemostatic variables that could identify those at risk would be important in reducing…
Updated Oct 29, 2026
HealthData.Gov
Fibroblast-like cells in the synovial lining (type B lining cells), stroma and pannus tissue are targeted by many signals, such as the following: ligands binding to cell surface receptors; lipid soluble, small molecular…
Updated Oct 29, 2026
HealthData.Gov
Excess information in complex ICU environments exceeds human decision making limits, increasing the likelihood of clinical errors. Explicit decision-support tools have favorable effects on clinician and patient outcomes…
Updated Oct 29, 2026
HealthData.Gov
Joint-specific and systemic autoreactivity in the development of inflammatory arthritis
Updated Oct 29, 2026
HealthData.Gov
Background Over 300 therapies have been proposed for premenstrual syndrome. To date there has been only one survey conducted in the UK of PMS treatments prescribed by GPs, a questionnaire-based study by the National…
Updated Oct 29, 2026
HealthData.Gov
Background Depending on their larval environment, female honeybees develop into either queens or workers. As in other polyphenisms, this developmental switch depends not on genomic differences between queens and workers…
Updated Oct 29, 2026
HealthData.Gov
Background Substance P (SP) is a peptide neurotransmitter found in central and peripheral nerves. SP is involved in the control of smooth muscle, inflammation and nociception. The amino acid sequence of SP is…
Updated Oct 29, 2026
HealthData.Gov
Background Several Trichoderma strains have been reported to be effective in controlling plant diseases, and the action of fungal hydrolytic enzymes has been considered as the main mechanism involved in the antagonistic…
Updated Oct 29, 2026
HealthData.Gov
Background We apply a new machine learning method, the so-called Support Vector Machine method, to predict the protein structural class. Support Vector Machine method is performed based on the database derived from…
Updated Oct 29, 2026
HealthData.Gov
Paper reports: Combating the invasion of intensive care literature
Updated Oct 29, 2026
HealthData.Gov
Background Because both public health surveillance and action are crucial, the authors initiated meetings at regional and national levels to assess and reform surveillance and action systems. These meetings emphasized…
Updated Oct 29, 2026
HealthData.Gov
Background Free radicals generated in biological systems by cigarette smoke (CS) inhalation can cause oxidative stress in tissues, resulting in lipid peroxidation (LPO). In view of the antioxidant properties of…
Updated Oct 29, 2026