HealthData.Gov
The clinical applicability of molecular cardiology has been questioned at length and by many clinical investigators. The congenital long QT syndrome (LQTS) provides an excellent example of how tight the relationship can…
Updated Oct 29, 2026
HealthData.Gov
Background Evidence suggests that both the migration and activation of neutrophils into the airway is of importance in pathological conditions such as pulmonary emphysema. In the present study, we describe in vivo…
Updated Oct 29, 2026
HealthData.Gov
The lung responds to a variety of insults in a remarkably consistent fashion but with inconsistent outcomes that vary from complete resolution and return to normal to the destruction of normal architecture and…
Updated Oct 29, 2026
HealthData.Gov
Background Vertebrate neural development requires precise coordination of cell proliferation and cell specification to guide orderly transition of mitotically active precursor cells into different types of post-mitotic…
Updated Oct 29, 2026
HealthData.Gov
Background The dinucleotide relative abundance profile can be regarded as a genomic signature because, despite diversity between species, it varies little between 50 kilobase or longer windows on a given genome. Both…
Updated Oct 29, 2026
HealthData.Gov
Hypothalamic–pituitary–adrenal underactivity has been reported in rheumatoid arthritis (RA). This phenomenon has implications with regard to the pathogenesis and treatment of the disease. The present study was designed…
Updated Oct 29, 2026
HealthData.Gov
Background Expression of transgenes in mice requires transcriptional regulatory elements that direct expression in a chosen cell type. Unfortunately, the availability of well-characterized promoters that direct…
Updated Oct 29, 2026
HealthData.Gov
Background Percutaneous nephrolithotomy is a minimally invasive intervention for renal stone disease. Complications, which are rare and usually presented as case reports, are diversified as the utilization of the…
Updated Oct 29, 2026
HealthData.Gov
Asthma is the most common chronic childhood disease in the developed nations, and is a complex disease that has high social and economic costs. Studies of the genetic etiology of asthma offer a way of improving our…
Updated Oct 29, 2026
HealthData.Gov
Comparative genomics provides at least three methods for identifying functional links between genes: examination of phylogenetic distributions, analysis of conserved proximity and observations of fusions of genes into a…
Updated Oct 29, 2026
HealthData.Gov
Background Increased BRCA1 and BRCA2 germline mutation rates have been reported in Ashkenazi Jewish women in North America, Europe and Israel, and have been mentioned as possibly related to a higher incidence of breast…
Updated Oct 29, 2026
HealthData.Gov
Background Biochemical and histochemical studies have both previously indicated plasma membrane-associated carbonic anhydrase (CA) activity in hepatocytes which has been assumed to be CA IV. However, immunohistochemical…
Updated Oct 29, 2026
HealthData.Gov
Agitation in the ICU: part one Anatomical and physiologic basis for the agitated state
Updated Oct 29, 2026
HealthData.Gov
Background Nitric oxide (NO) and oxygen free-radicals play an important part in the destruction of beta-cells in auto- immune diabetes although the precise mechanism of interaction is still not known. This study was…
Updated Oct 29, 2026
HealthData.Gov
Background Pyrazinamide (PZA) is among the first-line drugs for the treatment of tuberculosis. In vitro, it kills semidormant mycobacteria only at low pH. The purpose of this study was to compare PZA resistance with…
Updated Oct 29, 2026
HealthData.Gov
November's Institute of Medicine (IOM) report on medical errors has sparked debate among US health policy makers as to the appropriate response to the problem. Proposals range from the implementation of nationwide…
Updated Oct 29, 2026
HealthData.Gov
Objective To consider the problem of the calculation of number needed to treat (NNT) derived from risk difference, odds ratio, and raw pooled events shown to give different results using data from a review of nursing…
Updated Oct 29, 2026
HealthData.Gov
Crystalloid or colloid for resuscitation. Are we any the wiser?
Updated Oct 29, 2026
HealthData.Gov
Infective endocarditis remains a disease associated with high mortality in certain groups of patients, with death resulting primarily from central nervous system complications and congestive heart failure. Combined…
Updated Oct 29, 2026
HealthData.Gov
Background Only limited data exist on the costs of genital herpes (GH) in the USA. We estimated the economic burden of GH in the USA using two different costing approaches. Methods The first approach was a…
Updated Oct 29, 2026