HealthData.Gov
Background Expression of transgenes in mice requires transcriptional regulatory elements that direct expression in a chosen cell type. Unfortunately, the availability of well-characterized promoters that direct…
Updated Oct 29, 2026
HealthData.Gov
Background Percutaneous nephrolithotomy is a minimally invasive intervention for renal stone disease. Complications, which are rare and usually presented as case reports, are diversified as the utilization of the…
Updated Oct 29, 2026
HealthData.Gov
Objective To consider the problem of the calculation of number needed to treat (NNT) derived from risk difference, odds ratio, and raw pooled events shown to give different results using data from a review of nursing…
Updated Oct 29, 2026
HealthData.Gov
Crystalloid or colloid for resuscitation. Are we any the wiser?
Updated Oct 29, 2026
HealthData.Gov
Infective endocarditis remains a disease associated with high mortality in certain groups of patients, with death resulting primarily from central nervous system complications and congestive heart failure. Combined…
Updated Oct 29, 2026
HealthData.Gov
Background Only limited data exist on the costs of genital herpes (GH) in the USA. We estimated the economic burden of GH in the USA using two different costing approaches. Methods The first approach was a…
Updated Oct 29, 2026
HealthData.Gov
Background The purpose of this study was to investigate the association between secondhand smoke and the risk of developing a first event of acute coronary syndromes (ACS), i.e. acute myocardial infarction or unstable…
Updated Oct 29, 2026
HealthData.Gov
Background We assessed the nm23-H1 gene product expression and its relationship with lymphatic and blood vessel invasion in patients with esophageal squamous cell carcinoma. Methods Formalin-fixed and paraffin-embedded…
Updated Oct 29, 2026
HealthData.Gov
Results from the recent Dietary Approaches to Stop Hypertension (DASH)-Sodium trial provide the latest evidence concerning the effects of dietary patterns and sodium intake on blood pressure. Participants ate either the…
Updated Oct 29, 2026
HealthData.Gov
We propose that the phenomenon of X-chromosome inactivation in females may constitute a risk factor for loss of T-cell tolerance; specifically that skewed X-chromosome inactivation in the thymus may lead to inadequate…
Updated Oct 29, 2026
HealthData.Gov
Background The p53 protein is activated by genotoxic stress, oncogene expression and during senescence, p53 transcriptionally activates genes involved in growth arrest and apoptosis. p53 activation is regulated by…
Updated Oct 29, 2026
HealthData.Gov
Background Horses infected with Leptospira present several clinical disorders, one of them being recurrent uveitis. A common endpoint of equine recurrent uveitis is blindness. Serovar pomona has often been incriminated,…
Updated Oct 29, 2026
HealthData.Gov
Background It is known that proinflammatory and anti-inflammatory cytokines are released during and after cardiopulmonary bypass (CPB) in infants and children. Sex steroids are known to have immunomodulatory functions,…
Updated Oct 29, 2026
HealthData.Gov
Background Nuclear pore complexes (NPCs) are essential for facilitated, directional nuclear transport; however, the mechanism by which ~30 different nucleoporins (nups) are assembled into NPCs is unknown. We combined a…
Updated Oct 29, 2026
HealthData.Gov
Background Our aim was to explore the de-addiction properties of Delphinium denudatum Wall. in morphine dependent rats. Methods Charles Foster male albino rats were made morphine dependent by injecting morphine sulphate…
Updated Oct 29, 2026
HealthData.Gov
Background We are investigating a double transgenic rat (dTGR) model, in which rats transgenic for the human angiotensinogen and renin genes are crossed. These rats develop moderately severe hypertension but die of…
Updated Oct 29, 2026
HealthData.Gov
Background Physicians' perspectives regarding hepatitis C shape their approach to patient management. We used utility analysis to evaluate physicians' perceptions of hepatitis C-related health states (HS) and their…
Updated Oct 29, 2026
HealthData.Gov
Background In most endemic parts of the world, onchocerciasis (river blindness) control relies, or will soon rely, exclusively on mass treatment with the microfilaricide ivermectin. Worldwide eradication of the parasite…
Updated Oct 29, 2026
HealthData.Gov
Background A close association between Sst I polymorphism in the 3' untranslated region of the apolipoproteinC3 (APOC3) gene and levels of plasma triglycerides (TG) had been reported by different investigators.…
Updated Oct 29, 2026
HealthData.Gov
Background A tetracycline-regulated (conditional) system for RNA interference (RNAi) would have many practical applications. Such a strategy was developed using RNAi of the gene for phosphogluconate mutase (Pgm). Pgm is…
Updated Oct 29, 2026