Datasets

2,009 datasets

HealthData.Gov

Debate: Do all patients with heart failure require implantable defibrillators to prevent sudden death?

HTML

Updated Oct 29, 2026

HealthData.Gov

Norepinephrine-evoked pain in fibromyalgia. A randomized pilot study [ISRCTN70707830]

Background Fibromyalgia syndrome displays sympathetically maintained pain features such as frequent post-traumatic onset and stimuli-independent pain accompanied by allodynia and paresthesias. Heart rate variability…

HTML

Updated Oct 29, 2026

HealthData.Gov

Symptomatic hemorrhage after alteplase therapy not due to silent ischemia

Background Stroke thrombolysis-related intracerebral hemorrhage may occur remotely from the anatomical site of ischemia. One postulated mechanism for this is simultaneous multiple embolization with hemorrhage into a…

HTML

Updated Oct 29, 2026

HealthData.Gov

The evaluation of yeast derivatives as adjuvants for the immune response to the Bm86 antigen in cattle

Background The Gavac™ vaccine against the cattle tick Boophilus microplus has proven its efficacy in a large number of controlled and field experiments. However, this vaccine could be further improved by searching for…

HTML

Updated Oct 29, 2026

HealthData.Gov

Avian papillomaviruses: the parrot

Background An avian papillomavirus genome has been cloned from a cutaneous exophytic papilloma from an African grey parrot (Psittacus erithacus). The nucleotide sequence, genome organization, and phylogenetic position…

HTML

Updated Oct 29, 2026

HealthData.Gov

The Yersinia YopE and YopH type III effector proteins enhance bacterial proliferation following contact with eukaryotic cells

Background Several bacterial pathogens express antihost factors that likely decrease both their maximal growth rate (due to metabolic costs) as well as their mortality rate (by neutralizing host defenses). The…

HTML

Updated Oct 29, 2026

HealthData.Gov

How hyperglycemia promotes atherosclerosis: molecular mechanisms

Both type I and type II diabetes are powerful and independent risk factors for coronary artery disease (CAD), stroke, and peripheral arterial disease. Atherosclerosis accounts for virtually 80% of all deaths among…

HTML

Updated Oct 29, 2026

HealthData.Gov

Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice

Background The presynaptic protein α-synuclein is involved in a range of neurodegenerative diseases. Here we analyze potential compensatory mechanisms in α-synuclein null mutant mice. Furthermore, the findings reveal…

HTML

Updated Oct 29, 2026

HealthData.Gov

Management of acidosis: the role of buffer agents

HTML

Updated Oct 29, 2026

HealthData.Gov

Mesenchymal precursor cells in the blood of normal individuals

Mesenchymal precursor cells found in the blood (BMPCs) of normal persons adhere to plastic and glass and proliferate logarithmically in DMEM-20% fetal calf serum (FCS) without growth factors. They form cells with…

HTML

Updated Oct 29, 2026

HealthData.Gov

Debate: Does it matter how you lower blood pressure?

Whether it matters how pressure is lowered has been debated since antihypertensive drugs proved to prevent cardiovascular events. However, in clinical trials, while the stroke benefit predicted by a given difference in…

HTML

Updated Oct 29, 2026

HealthData.Gov

Abundant protein domains occur in proportion to proteome size

Background Conserved domains in proteins have crucial roles in protein interactions, DNA binding, enzyme activity and other important cellular processes. It will be of interest to determine the proportions of genes…

HTML

Updated Oct 29, 2026

HealthData.Gov

The stressed synovium

This review focuses on the mechanisms of stress response in the synovial tissue of rheumatoid arthritis. The major stress factors, such as heat stress, shear stress, proinflammatory cytokines and oxidative stress, are…

HTML

Updated Oct 29, 2026

HealthData.Gov

Heat stress is associated with decreased lactic acidemia in rat sepsis

Background: Elevated plasma lactate has been shown to correlate with mortality in patients with septic shock. Heat stress prior to sepsis has resulted in reduction in acute lung injury and mortality. We investigated…

HTML

Updated Oct 29, 2026

HealthData.Gov

The neuropharmacology of upper airway motor control in the awake and asleep states: implications for obstructive sleep apnoea

Obstructive sleep apnoea is a common and serious breathing problem that is caused by effects of sleep on pharyngeal muscle tone in individuals with narrow upper airways. There has been increasing focus on delineating…

HTML

Updated Oct 29, 2026

HealthData.Gov

Characterization of adjacent breast tumors using oligonucleotide microarrays

Background Current methodology often cannot distinguish second primary breast cancers from multifocal disease, a potentially important distinction for clinical management. In the present study we evaluated the use of…

HTML

Updated Oct 29, 2026

HealthData.Gov

Cell density related gene expression: SV40 large T antigen levels in immortalized astrocyte lines

Background Gene expression is affected by population density. Cell density is a potent negative regulator of cell cycle time during exponential growth. Here, we asked whether SV40 large T antigen (Tag) levels, driven by…

HTML

Updated Oct 29, 2026

HealthData.Gov

A critical appraisal of clinical practice guidelines for the treatment of lower-limb osteoarthritis

Clinical practice guidelines are important tools to assist clinical decision-making. Recently, several guidelines addressing the management of osteoarthritis (OA) have been published. Clinicians treating patients with…

HTML

Updated Oct 29, 2026

HealthData.Gov

Intraocular pressure in genetically distinct mice: an update and strain survey: Correction

HTML

Updated Oct 29, 2026

HealthData.Gov

Bone loss: Epidemiology of bone loss

Bone loss occurs when the cellular events of bone formation are quantitatively larger than bone formation. This manuscript discusses the measurement of bone loss, occurrence in the population, risk factors and…

HTML

Updated Oct 29, 2026