Datasets

2,009 datasets

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Managing death in the intensive care unit: bringing back the humanity

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Updated Oct 29, 2026

HealthData.Gov

The inflammatory infiltrate in the acute stage of the dextran sulphate sodium induced colitis: B cell response differs depending on the percentage of DSS used to induce it

Background Experimental colitis with features similar to inflammatory bowel disease (IBD) has initially been described. A detailed analysis of inflammatory cells has not yet been described. Therefore in this study we…

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Updated Oct 29, 2026

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Proteinase-3 as the major autoantigen of c-ANCA is strongly expressed in lung tissue of patients with Wegener's granulomatosis

Proteinase-3 (PR-3) is a neutral serine proteinase present in azurophil granules of human polymorphonuclear leukocytes and serves as the major target antigen of antineutrophil cytoplasmic antibodies with a cytoplasmic…

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Updated Oct 29, 2026

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Adhesion molecules in different treatments of acute myocardial infarction

Background: Tissue damage after ischemia and reperfusion involves leukocyte endothelial interactions mediated by cell adhesion molecules. This study was designed to determine the time course of soluble adhesion…

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Updated Oct 29, 2026

HealthData.Gov

Genomic comparisons among

Background Insertion Sequence (IS) elements are mobile genetic elements widely distributed among bacteria. Their activities cause mutations, promoting genetic diversity and sometimes adaptation. Previous studies have…

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Updated Oct 29, 2026

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Diagnostic strategies for C-reactive protein

Background Serum C-reactive protein (CRP) has been identified in prospective epidemiological research as an independent risk marker for cardiovascular disease. In this paper, short-term biological variation of CRP is…

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Updated Oct 29, 2026

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Reviewing the reviewers: the vague accountability of research ethics committees

The role of research ethics committees (RECs) is currently strained by increases in the number of protocols that are in need of review, the scientific and funding complexities of the protocols, and a lack of clear…

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Updated Oct 29, 2026

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Reliability of race assessment based on the race of the ascendants: a cross-sectional study

Background Race is commonly described in epidemiological surveys based on phenotypic characteristics. Training of interviewers to identify race is time-consuming and self identification of race might be difficult to…

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Updated Oct 29, 2026

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Pacing in congestive heart failure

Despite the major advances in medical drug therapy, heart failure remains a syndrome associated with high mortality and morbidity. Biventricular or left ventricular (LV) short atrioventricular (AV) delay pacing is being…

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Updated Oct 29, 2026

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Variation in red cell transfusion practice in the intensive care unit: a multicentre cohort study

Objectives: To determine the degree of interinstitutional transfusion practice variation and reasons why red cells are administered in critically ill patients. Study design: Multicentre cohort study combined with a…

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Updated Oct 29, 2026

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A prospective study of rural drinking water quality and acute gastrointestinal illness

Background This study examined the relationship between the bacteriological contamination of drinking water from private wells and acute gastrointestinal illness (AGII), using current government standards for safe…

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Updated Oct 29, 2026

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Klippel-Feil syndrome – the risk of cervical spinal cord injury: A case report

Background Klippel-Feil syndrome is defined as congenital fusion of two or more cervical vertebrae and is believed to result from faulty segmentation along the embryo's developing axis during weeks 3–8 of gestation.…

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Updated Oct 29, 2026

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Mechanical ventilation: lessons from the ARDSNet trial

The acute respiratory distress syndrome (ARDS) is an inflammatory disease of the lungs characterized clinically by bilateral pulmonary infiltrates, decreased pulmonary compliance and hypoxemia. Although supportive care…

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Updated Oct 29, 2026

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Leptin in septic arthritis: decreased levels during infection and amelioration of disease activity upon its administration

Weight loss is typically found during severe infections, e.g. septic arthritis. The aim of our study was to evaluate the role of leptin, regulator of food intake and energy expenditure, for the development of…

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Updated Oct 29, 2026

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Screening for sequence-specific RNA-BPs by comprehensive UV crosslinking

Background Specific cis-elements and the associated trans-acting factors have been implicated in the post-transcriptional regulation of gene expression. In the era of genome wide analyses identifying novel trans-acting…

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Updated Oct 29, 2026

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Vitamin D receptor initiation codon polymorphism influences genetic susceptibility to type 1 diabetes mellitus in the Japanese population

Background Vitamin D has been shown to exert manifold immunomodulatory effects. Type 1 diabetes mellitus (T1DM) is regarded to be immune-mediated and vitamin D prevents the development of diabetes in the NOD mouse. We…

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Updated Oct 29, 2026

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CMV infection of liver transplant recipients: comparison of antigenemia and molecular biology assays

Background CMV is a major clinical problem in transplant recipients. Thus, it is important to use sensitive and specific diagnostic techniques to rapidly and accurately detect CMV infection and identify patients at risk…

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Updated Oct 29, 2026

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Research that influences policy and practice – characteristics of operational research to improve malaria control in Mpumalanga Province, South Africa

Background Much communicable disease control research has had little impact on local control programme policy and practice for want of an operational component. The operational research model – the systematic search for…

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Updated Oct 29, 2026

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Jejunogastric intussusception presented with hematemesis: a case presentation and review of the literature

Background Jejunogastric intussusception (JGI) is a rare but potentially very serious complication of gastrectomy or gastrojejunostomy. To avoid mortality early diagnosis and prompt surgical intervention is mandatory.…

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Updated Oct 29, 2026

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A49T, V89L and TA repeat polymorphisms of steroid 5α-reductase type II and breast cancer risk in Japanese women

Background Breast cancer is hormone related, as are cancers of the endometrium, ovary, and prostate. Several studies have suggested that higher extracellular levels of androgens are associated with breast cancer risk,…

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Updated Oct 29, 2026