HealthData.Gov
Articular cartilage has limited capacity to repair. Defects greater than 3 mm heal with formation of inferior fibrous cartilage. Therefore, many attempts have been made to find the ideal graft for larger cartilage…
Updated Oct 29, 2026
HealthData.Gov
Immotile cilia syndrome (ICS) or primary ciliary dyskinesia (PCD) is an autosomal recessive disorder in humans in which the beating of cilia and sperm flagella is impaired. Ciliated epithelial cell linings are present…
Updated Oct 29, 2026
HealthData.Gov
The association ofChlamydia pneumoniaewith atherosclerosis is controversial. We investigated the presence ofC. pneumoniaeand otherChlamydiaspp. in atheromatous carotid artery tissue.
Updated Oct 29, 2026
HealthData.Gov
We have previously reported that altered culture conditions (a broth media with shaking) could induce a strain ofHelicobacter pylorito assume a long spiral morphology resembling that described forHelicobacter…
Updated Oct 29, 2026
HealthData.Gov
The synovium lines the noncartilaginous surfaces of the diarthrodial joints, and synovial tissue is also found in tendon sheaths and bursae [1]. Several rheumatic diseases are characterized by synovial inflammation. In…
Updated Oct 29, 2026
HealthData.Gov
The human eye is poor at recognizing hypoxemia. Even under idealconditions, skilled observers cannot consistently detect hypoxemia until theoxygen (O2) saturation is below 80% [1]. Thedifficulty that physicians have in…
Updated Oct 29, 2026
HealthData.Gov
ManyHelicobacter pylorieradication regimens have been described. There are little data reporting their efficacy or integration in routine clinical practice. The overall results of eradication therapy in a cohort of…
Updated Oct 29, 2026
HealthData.Gov
Macrophages, osteoclasts, dendritic cells, and microglia are highly specialized cells that belong to the mononuclear phagocyte system. Functional and phenotypic heterogeneity within the mononuclear phagocyte system may…
Updated Oct 29, 2026
HealthData.Gov
Germline mutations in the tumor suppressorPTENpredispose human beings to breast cancer, and genetic and epigenetic alterations ofPTENare also detected in sporadic human breast cancer. GermlinePtenmutations in mice lead…
Updated Oct 29, 2026
HealthData.Gov
We are delighted to welcome you to the first printed issue ofArthritis Research, a publication that has already existed on the Internet for the last few months. This fact alone is an indication that we are beginning a…
Updated Oct 29, 2026
HealthData.Gov
The Mitotic Exit Network (MEN) proteins – including the protein kinase Cdc15 and the protein phosphatase Cdc14 – are essential for exit from mitosis inSaccharomyces cerevisiae.To identify downstream targets of the MEN,…
Updated Oct 29, 2026
HealthData.Gov
Blood substitutes have long been sought after, and artificial oxygen carriers may soon become a reality. Despite increased safety of allogeneic blood in terms of transmission of infectious diseases [1], avoiding…
Updated Oct 29, 2026
HealthData.Gov
Previous studies have shown that several agents that stimulate heptahelical G-protein coupled receptors activate the extracellular signal regulated kinases ERK1 (p44mapk) and ERK2 (p42mapk) in hepatocytes. The molecular…
Updated Oct 29, 2026
HealthData.Gov
In this issue of the journal, Steinwaldet al[1] extend limited clinical studies and report an animal experiment showing that calcitonin precursors (predominantly procal-citonin) are elevated in proportion to the…
Updated Oct 29, 2026
HealthData.Gov
Mycobacterium aviumsubspeciesparatuberculosis(M. paratuberculosis) is a facultative intracellular pathogen that resides within host macrophages during infection of ruminant animals. We examined survival ofM.…
Updated Oct 29, 2026
HealthData.Gov
I am delighted to welcome you to the first printed issue ofRespiratory Research. This new journal, available both on the World Wide Web and in print, will provide timely reviews and rapid publication of primary research…
Updated Oct 29, 2026
HealthData.Gov
This year marks the 100th anniversary of the discovery by Camillo Golgi of an “internal reticular apparatus” in eukaryotic cells. The cover figure, from a classic paper by Friend and Murray (Friend, D.S., and Murray,…
Updated Oct 29, 2026
HealthData.Gov
Within the family of green fluorescent protein (GFP) homologs, one can mark two main groups, specifically, fluorescent proteins (FPs) and non-fluorescent or chromoproteins (CPs). Structural background of differences…
Updated Oct 29, 2026
HealthData.Gov
The ability of transfected synthetic small interfering (si) RNAs to suppress the expression of specific transcripts has proved a useful technique to probe gene function in mammalian cells. However, high production costs…
Updated Oct 29, 2026
HealthData.Gov
It is a rare treat when a drug discovery program teaches us something about the biology of the process that it attempts to modulate. The paper by Maria Frank-Kamenetsky and colleagues in this issue of theJournal of…
Updated Oct 29, 2026