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BLAST (Basic Local Alignment Search Tool) finds regions of similarity between biological sequences. BLAST includes several specialized search interfaces: SmartBLAST, Primer-BLAST, Global Align, CD-Search, IgBLAST,…
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E-utilities (Entrez Programming Utilities) are a set of eight server-side programs that provide a stable interface into the Entrez query and database system at the National Center for Biotechnology Information (NCBI).
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GRAF (Genetic Relationship and Fingerprinting) is a C++ program that quickly finds the closely related subjects, infers subject ancestry, determines subject sexes using genotypes and compares the results derived from…
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A public domain quality assurance software package that facilitates the assessment of multiplex short tandem repeat (STR) DNA profiles based on laboratory-specific protocols.
HealthData.Gov
A stand-alone application for viewing 3-dimensional structures from NCBI Entrez retrieval service. Runs on Windows, Macintosh, and UNIX and can be configured to receive data from most popular Web browsers.
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Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific…
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A utility for computing alignment of proteins to genomic nucleotide sequence based on a variation of the Needleman Wunsch global alignment algorithm and specifically accounts for introns and splice signals.
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TSA is an archive of computationally assembled transcript sequences from primary data such as ESTs and Next Generation Sequencing Technologies. The overlapping sequence reads from a complete transcriptome are assembled…
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An application for navigating RxNorm drugs. This applications displays relations among drug entities in RxNorm and provides additional information about RxNorm drugs, including drug classes, pill images and drug-drug…
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Three dimensional structures provide a wealth of information on the biological function and the evolutionary history of macromolecules. They can be used to examine sequence-structure-function relationships,…
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A single entry point for users to link to and find information about data submission processes at NCBI.
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This genetic variation services interconvert and transform short genetic variants between HGVS expressions, VCF format, and the new SPDI (Sequence Position Deletion Insertion) format, based on alignment datasets used by…
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The Sequence Read Archive (SRA) stores sequencing data from the next generation of sequencing platforms including Roche 454 GS System®, Illumina Genome Analyzer®, Life Technologies AB SOLiD System®, Helicos Biosciences…
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A graphical analysis tool that finds all open reading frames in a user's sequence or in a sequence already in the database.
HealthData.Gov
A JavaScript package that can be included in webpages or programs and used for validating and converting unit expressions from the Unified Code for Units of Measure (UCUM).
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Genetic Testing Registry (GTR) is a free, centralized voluntary registry of comprehensive genetic test information covering clinical and research tests for Mendelian disorders and drug responses including multigenic,…
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Constraint-Based Multiple Alignment Tool (COBALT) is a protein multiple sequence alignment tool that finds a collection of pairwise constraints derived from conserved domain database, protein motif database, and…
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CDTree is a stand-alone application for classifying protein sequences and investigating their evolutionary relationships. CDTree can import, analyze and update existing Conserved Domain (CDD) records and hierarchies,…
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Database of Short Genetic Variations (dbSNP) contains human single nucleotide variations, microsatellites, and small-scale insertions and deletions along with publication, population frequency, molecular consequence,…
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Quickly identifying segments of a nucleic acid sequence that may be of vector origin.