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NO-independent regulatory site of direct sGC stimulators like YC-1 and BAY 41-2272
Background The most important receptor for nitic oxide is the soluble guanylate cyclase (sGC), a heme containing heterodimer. Recently, a pyrazolopyridine derivative BAY 41-2272, structurally related to YC-1, was…
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Updated Oct 29, 2026