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Background We would expect information on adverse drug reactions in randomised clinical trials to be easily retrievable from specific searches of electronic databases. However, complete retrieval of such information may…
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Background The "integrated safety report" of the drug registration files submitted to health authorities usually summarizes the rates of adverse events observed for a new drug, placebo or active control drugs by pooling…
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Background Decisions on treatment are guided, not only by the potential for benefit, but also by the nature and severity of adverse drug reactions. However, some researchers have found numerous deficiencies in trial…
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Qinlock (ripretinib) is an oral prescription tablet that acts as a kinase inhibitor, targeting enzymes like KIT and PDGFR alpha to help manage certain cancers. Manufactured by Deciphera Pharmaceuticals, LLC, it comes in…
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Clomipramine Hydrochloride Capsules are a generic prescription medication used as a tricyclic antidepressant. Manufactured by Lupin Pharmaceuticals, Inc., it comes in 25 mg, 50 mg, and 75 mg strengths for oral use. This…
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Amantadine Hydrochloride is a prescription medication available as an oral syrup (50 mg/5 mL) used to treat certain types of influenza (flu) by inhibiting the virus. Manufactured by Patrin Pharma, Inc., under…
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Imodium A-D is an over-the-counter medication containing loperamide hydrochloride, used to relieve symptoms of diarrhea in adults and children over 6 years old. It comes as an oral solution (1 mg per 7.5 mL) and works…
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Accuretic is a prescription medication combining quinapril (an ACE inhibitor) and hydrochlorothiazide (a diuretic) to treat high blood pressure. It comes as oral tablets in various strengths, manufactured by Parke-Davis…
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RALDESY is a prescription oral solution containing trazodone hydrochloride (10 mg/mL), a serotonin reuptake inhibitor used to treat major depressive disorder. Manufactured by Validus Pharmaceuticals LLC and approved…
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Idhifa (enasidenib mesylate) is a prescription oral tablet that inhibits the IDH2 enzyme, used to treat adults with relapsed or refractory acute myeloid leukemia (AML) who have an IDH2 mutation. Available in 50mg and…
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Erythromycin Ethylsuccinate is an antibiotic used to treat bacterial infections. It's available as an oral suspension in strengths like 200 mg or 400 mg per 5 mL, packaged in 100 mL bottles. Manufactured by Cadila…
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Nadolol is a generic beta-adrenergic blocker medication available as oral tablets in 20mg, 40mg, and 80mg strengths. Manufactured by Aurobindo Pharma Limited, it is prescribed to treat conditions like high blood…
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Carvedilol Phosphate is a generic prescription medication available as extended-release oral capsules in strengths of 10mg, 20mg, 40mg, and 80mg. It acts as an alpha and beta adrenergic blocker, commonly used to treat…
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Losartan Potassium is a prescription medication that helps lower high blood pressure and treat heart failure by blocking substances that tighten blood vessels. Available as oral tablets in 25mg, 50mg, and 100mg…
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XURIDEN is a prescription drug containing uridine triacetate, available as oral granules (2g per packet). Manufactured by BTG International Inc, it's a pyrimidine analog used in medical emergencies, such as treating…
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Olanzapine is a generic atypical antipsychotic medication used to treat schizophrenia and bipolar disorder. Manufactured by Aurobindo Pharma Ltd., it comes as orally disintegrating tablets in strengths of 5 mg, 10 mg,…
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Acyclovir is a prescription topical ointment containing 5% acyclovir, used to treat outbreaks of herpes simplex virus infections like cold sores on the lips and face. It works by stopping the virus from multiplying.…
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Prucalopride Succinate is a prescription medication available as oral tablets in 1 mg and 2 mg strengths, manufactured by Novadoz Pharmaceuticals LLC under ANDA218177. It acts as a serotonin-4 receptor agonist to treat…
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Pregabalin is a generic prescription medication available as oral capsules in strengths of 25mg, 50mg, 75mg, 100mg, 150mg, 200mg, 225mg, and 300mg. Manufactured by Torrent Pharmaceuticals Limited under ANDA206942, it is…
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Nitrofurantoin Macrocrystals is a prescription antibiotic available as 50mg and 100mg oral capsules, manufactured by Lupin Pharmaceuticals, Inc. It belongs to the nitrofuran class and is used to treat certain bacterial…