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Mycobacterium aviumsubspeciesparatuberculosis(M. paratuberculosis) is a facultative intracellular pathogen that resides within host macrophages during infection of ruminant animals. We examined survival ofM.…
Updated Oct 29, 2026
HealthData.Gov
Early diagnosis of wound colonisation or prediction of wound sepsis provides an opportunity for therapeutic intervention. There is need for qualitative and quantitative tests that are more rapid than bacterial…
Updated Oct 29, 2026
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Articular cartilage has limited capacity to repair. Defects greater than 3 mm heal with formation of inferior fibrous cartilage. Therefore, many attempts have been made to find the ideal graft for larger cartilage…
Updated Oct 29, 2026
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The human eye is poor at recognizing hypoxemia. Even under idealconditions, skilled observers cannot consistently detect hypoxemia until theoxygen (O2) saturation is below 80% [1]. Thedifficulty that physicians have in…
Updated Oct 29, 2026
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We have previously reported that altered culture conditions (a broth media with shaking) could induce a strain ofHelicobacter pylorito assume a long spiral morphology resembling that described forHelicobacter…
Updated Oct 29, 2026
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The association ofChlamydia pneumoniaewith atherosclerosis is controversial. We investigated the presence ofC. pneumoniaeand otherChlamydiaspp. in atheromatous carotid artery tissue.
Updated Oct 29, 2026
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Immotile cilia syndrome (ICS) or primary ciliary dyskinesia (PCD) is an autosomal recessive disorder in humans in which the beating of cilia and sperm flagella is impaired. Ciliated epithelial cell linings are present…
Updated Oct 29, 2026
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This year marks the 100th anniversary of the discovery by Camillo Golgi of an “internal reticular apparatus” in eukaryotic cells. The cover figure, from a classic paper by Friend and Murray (Friend, D.S., and Murray,…
Updated Oct 29, 2026
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I am delighted to welcome you to the first printed issue ofRespiratory Research. This new journal, available both on the World Wide Web and in print, will provide timely reviews and rapid publication of primary research…
Updated Oct 29, 2026
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The synovium lines the noncartilaginous surfaces of the diarthrodial joints, and synovial tissue is also found in tendon sheaths and bursae [1]. Several rheumatic diseases are characterized by synovial inflammation. In…
Updated Oct 29, 2026
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The adaptor protein p130Cas(Cas) has been shown to be involved in different cellular processes including cell adhesion, migration and transformation. This protein has a substrate domain with up to 15 tyrosines that are…
Updated Oct 29, 2026
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Tumor Necrosis Factor-α (TNF-α) has been implicated in the pathogenesis of insulin resistance and obesity. The increased expression of TNF-α in adipose tissue has been shown to induce insulin resistance, and a…
Updated Oct 29, 2026
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Spontaneous premature ovarian failure presents most commonly with secondary amenorrhea. Young women with the disorder are infertile and experience the symptoms and sequelae of estrogen deficiency. The mechanisms that…
Updated Oct 29, 2026
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In this issue of the journal, Steinwaldet al[1] extend limited clinical studies and report an animal experiment showing that calcitonin precursors (predominantly procal-citonin) are elevated in proportion to the…
Updated Oct 29, 2026
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The ability of transfected synthetic small interfering (si) RNAs to suppress the expression of specific transcripts has proved a useful technique to probe gene function in mammalian cells. However, high production costs…
Updated Oct 29, 2026
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ManyHelicobacter pylorieradication regimens have been described. There are little data reporting their efficacy or integration in routine clinical practice. The overall results of eradication therapy in a cohort of…
Updated Oct 29, 2026
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We are delighted to welcome you to the first printed issue ofArthritis Research, a publication that has already existed on the Internet for the last few months. This fact alone is an indication that we are beginning a…
Updated Oct 29, 2026
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The Mitotic Exit Network (MEN) proteins – including the protein kinase Cdc15 and the protein phosphatase Cdc14 – are essential for exit from mitosis inSaccharomyces cerevisiae.To identify downstream targets of the MEN,…
Updated Oct 29, 2026
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WhenArthritis Researchwas launched in 1999 the publishers and ourselves took the innovative decision to make all primary research articles available to everyone for free through the journal's own…
Updated Oct 29, 2026
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Macrophages, osteoclasts, dendritic cells, and microglia are highly specialized cells that belong to the mononuclear phagocyte system. Functional and phenotypic heterogeneity within the mononuclear phagocyte system may…
Updated Oct 29, 2026