Datasets

2 datasets

HealthData.Gov

Glycerol restores heat-induced p53-dependent apoptosis of human glioblastoma cells bearing mutant p53

Background We have previously reported that glycerol acts as a chemical chaperone to restore the expression of WAF1 in some human cancer cell lines bearing mutant p53. Since the expression of WAF1 is up-regulated by…

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Updated Oct 29, 2026

HealthData.Gov

Mitotic death: a mechanism of survival? A review

Mitotic death is a delayed response of p53 mutant tumours that are resistant to genotoxic damage. Questions surround why this response is so delayed and how its mechanisms serve a survival function. After uncoupling…

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Updated Oct 29, 2026